Summer 2016
> Health Sciences
> MLSC.5800
> 031
Course No: MLSC.5800-031; SIS Class Nbr: 2720; SIS Term: 2540
Course Status: Registration Closed
Course Description
This course begins with a review of basic molecular genetics, followed by a discussion of the human genome project, including the application of its technology to the management of genetic diseases. Laboratory techniques used to analyze pre- and postnatal tissue samples is described, including RFLP-Southern blot technology, various forms of PCR, VNTR assessment, and gene expression analysis by microchip arrays. Cloning and stem cell analysis follows, including the ethical, legal, and social issues surrounding these areas. Cancer genetics and cytogenesis is presented, with emphasis on molecular changes that lead to the onset of cancer. Genetic treatments for cancer are reviewed. Gene therapy is detailed, including the historical perspective, gene therapy vectors and their mode of action, and the newest methods for treating genetic disorders at the DNA level. Structural and functional genomics follows, centering around the creation of pharmaceuticals solely based on the genetic basis of diseases. This is followed by a detailed section on epigenetics and its application to diagnosis and prediction of disease phenotypes. GWAS (Genome Wide Association Studies) is detailed as it applies to diagnosis in both individuals and entire populations. The course ends with a discussion of the human proteome project, and the human transcriptome project, including goals and objectives, current progress, and the storage of data in complex bioinformatic databases.
Prerequisites, Notes & Instructor
- Prerequisites: Students with a CSCE career need permission to take Graduate Level Courses.
- Credits: 3; Contact Hours: 3
- Instructor: Theodore Namm
-
UMass Lowell Bookstore
When Offered & Tuition
- Online Course
- 2016 Summer: May 16 to Aug 06
- Chat Hours: Thu 7-8pm*
- Course Level: Graduate
-
Tuition: $1710
- Note: There is a $30 per semester registration fee for credit courses.
*Chat Hours provide an opportunity for the instructor and students to communicate
in "real time". It is an informative and interactive session where course related questions, answers,
and discussions take place. While student attendance during chat hours is not required, it is highly recommended.
Weekly chat sessions are archived for students who are not able to participate in the live chat sessions at the
scheduled times.
Every effort has been made to ensure the accuracy of the information presented in this catalog. However, the Division of Graduate, Online & Professional Studies reserves the right to implement new rules and regulations and to make changes of any nature to its program, calendar, procedures, standards, degree requirements, academic schedules (including, without limitations, changes in course content and class schedules), locations, tuition and fees. Whenever possible, appropriate notice of such changes will be given before they become effective.