Fall 2025
> Engineering/Engineering Technology
> CHEN.5420
> 031V
Course No: CHEN.5420-031V; SIS Class Nbr: 11944; SIS Term: 3510
Course Status: Open
Course Description
Metabolic engineering combines aspects of chemical engineering, biochemistry, and synthetic biology, which aims towards modification of cellular processes and metabolic networks to achieve biomanufacturing of fuels, chemicals, food ingredients, and pharmaceuticals. This course aims to provide fundamental and advanced knowledge in engineering microbial strains for bioproduction through synthetic biology and metabolic engineering. The lecture sessions will cover the fundamental knowledge of cellular metabolic pathways, basic principles of metabolic engineering, metabolic flux analysis, regulation of metabolic pathways, applications of metabolic engineering, and biosynthesis of primary and secondary metabolites. Basic and advanced genetic techniques for strain engineering, including CRISPR gene editing technology, will also be presented.
Prerequisites, Notes & Instructor
- Prerequisites: Co-req: BIOL.2010 General Microbiology, or BIOL.2100 Biology for Engineers, and CHEM.4500 Introduction to Biochemistry, or Permission of Instructor.
- Section Notes: Virtual Classroom Course
- Credits: 3; Contact Hours: 3
- Instructor: Dongming Xie
-
UMass Lowell Bookstore
When Offered & Tuition
- W | 3:30 PM-6:20 PM ET Online
- 2025 Fall: Sep 03 to Dec 20
- Course Level: Graduate
-
Tuition: $1830
- Note: There is a $30 per semester registration fee for credit courses.
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